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Results of DCM. ( A ) Bayesian Model Selection of all our models showing that model 14 is clearly the strongest. ( B ) Illustration and coupling parameters of our winning model (model 14). The net coupling parameter of the VIM>VIM self-connection is determined by the intrinsic coupling times modulation by dopamine (Ep.A × Ep.B = 0.921 × 1.002). MC = motor cortex.

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Results of DCM. ( A ) Bayesian Model Selection of all our models showing that model 14 is clearly the strongest. ( B ) Illustration and coupling parameters of our winning model (model 14). The net coupling parameter of the VIM>VIM self-connection is determined by the intrinsic coupling times modulation by dopamine (Ep.A × Ep.B = 0.921 × 1.002). MC = motor cortex.

We proceeded to investigate the estimated parameters of this winning model. The modulation by dopamine of the VIM>VIM self-connection as estimated by DCM (i.e. Ep.B parameter) is a scaling parameter of the fixed connection strength (i.e. Ep.A parameter) where a value >1 indicates an increase of the inhibitory self-connection strength ( Zeidman, 2015 ). A one-sample t -test showed that this scaling parameter was not significantly different from 1 across the whole group [ t (14); mean = 1.002, SD = 0.013, P = 0.48], indicating no significant modulatory effect of dopamine on the self-connection. This is perhaps at first surprising, because this model clearly outperformed a null-model with no modulatory effect of dopamine. However, this finding emphasizes the power of Bayesian model comparison: the combination of the absence of a significant directional effect at the parameter level across the group in context of positive model evidence indicates that this parameter is highly variable across individuals, yet meaningful. Indeed, we observed a significant relationship between the dopaminergic modulation of the inhibitory VIM self-connection (Ep.B) and the clinical dopamine response of resting tremor (R = 0.56, P = 0.03; Fig. 4 A). This indicates that dopamine increased the inhibitory VIM self-coupling most in patients with clinically more dopamine-responsive tremor.

Figure 4
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Brain–behaviour relationship. Figure displaying the correlation between the dopaminergic modulation of the inhibitory VIM self-connection (Ep.B) as estimated by DCM and the clinical dopamine responsiveness of resting tremor ( A ), bradykinesia ( B ), and rigidity ( C ) based on UPDRS differences score (OFF minus ON). Only dopamine responsiveness of tremor was significantly correlated with the Ep.B parameter, even when controlling for the dopamine responsiveness of the other two symptoms (partial correlation, R = 0.56, 0.046). *Significant effect.

Figure 4
View large Download slide

Brain–behaviour relationship. Figure displaying the correlation between the dopaminergic modulation of the inhibitory VIM self-connection (Ep.B) as estimated by DCM and the clinical dopamine responsiveness of resting tremor ( A ), bradykinesia ( B ), and rigidity ( C ) based on UPDRS differences score (OFF minus ON). Only dopamine responsiveness of tremor was significantly correlated with the Ep.B parameter, even when controlling for the dopamine responsiveness of the other two symptoms (partial correlation, R = 0.56, 0.046). *Significant effect.

Next, we tested whether this brain-behaviour relationship was specific for tremor. There were no correlations between the dopaminergic modulation of the inhibitory VIM self-connection (Ep.B) and the clinical dopamine response of bradykinesia (R = 0.06, P = 0.83; Fig. 4 B) or rigidity (R = 0.42, P = 0.11; Fig. 4 C). Furthermore, when we calculated partial correlations between each clinical symptom and dopaminergic modulation of the inhibitory VIM self-connection (Ep.B)—while controlling for the other two symptoms—we found a significant partial correlation only for resting tremor (R = 0.56, P = 0.046), but not for bradykinesia or rigidity.

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STEMosaur: #1 Smart Toy for Kids
Smart companions that engage kids in interactive play while building coding and engineering skills!
Project Owner
New York City, United States
1 Campaign
$187,782 USD total funds raised
funded on November 20, 2017
Production Stage
Learn more
Meet STEMosaur: The customizable smart toy that doubles as a learning tool for kids. From telling jokes to providing answers to questions in a range of subjects, STEMosaur provides educational and kid-friendly fun for the whole family. STEMosaur is also equipped with an easy-to-use coding panel that allows children to learn coding basics and code content into their very own toy!
Production Stage
Learn more

STEMosaur is a family-friendly smart toy that engages kids with science, technology, engineering, mathematics and coding-basics in a new and fun way. We are changing the way kids learn forever!

Learning begins with a hands-on construction exercise that allows children to understand and enjoy the process of assembling their STEMosaur. Once assembled, STEMosaur is immediately capable of holding conversation, telling jokes, and playing games that inspire imagination and creativity.

STEMosaur engages users with kid-friendly content that is educational and fun. Kids can play games with their STEMosaur, ask it endless questions and even try meditation. As kids get older, their STEMosaur will grow with them, adapting to their unique learning level to ensure that they are consistently challenged on a wide range of subjects.

With STEMosaur, our team focused on finding the perfect intersection between having fun with your kids and actively helping them learn important skills such an coding, engineering and more. Being actively engaged and having fun while learning has a positive effect on motivation levels, determining what we learn and how much we retain from those experiences. Learning isn’t a one-way street. It requires repetition, motivationand dedication.

STEMosaur is ideal for kids ages 7 and up, but younger children can also enjoy STEMosaur’s educational benefits with the help of a grown-up. The toy is fun for the whole family, engaging parents and kids alike in interactive STEM learning.

Everything from STEMosaur’s simple assembly instructions to its built-in coding kit are made especially for kids, creating a multi-dimensional learning experience that helps children to develop positive associations with STEM subjects right from the beginning.

Our creative team here at CogniToys, along with our network of educators, keeps educational learning fresh and exciting through our ever-growing content base sothe fun never ends.

STEMosaur automatically receives updates through its cloud-based software on a weekly basis. No additional action is required for these updates by the parent or child. All you need to do is connect your STEMosaur to Wi-Fi during the initial setup of your toy.

On average, kids ask more than 300 questions per day. STEMosaur helps to satisfy this endless curiosity by engaging users in intuitive conversation, as well as reinforcing conversational confidence. This interactive smart toy can answer all kinds of questions on subjects like math, science, geography and astronomy so kids can learn while they play.

As your child learns and grows, so does their buddy! STEMosaur can advance with the learning curve of your child so content remains relevant, engaging and age appropriate. It’s like having your own personal tutor to learn from and play with—ensuring a positive educational experience at all times.

From its very first interaction, STEMosaur teaches children fundamental engineering principles. Through the toy’s construction kit, STEMosaur makes learning about engineering and construction an exciting and rewarding experience.

Set-up is easy with our kid-friendly construction guide. With the help of an adult, your STEMosaur will be up and roaring in no time!

Research has shown that STEM education at an early age nurtures critical thinking skills and lifelong civic engagement, regardless of future career paths and education plans. These lifelong benefits are reinforced by STEMosaur, a playtime buddy that gets your child excited about discovering STEM subjects, like coding.

STEMosaur’s coding panel enables kids to code content into their very own toy. By enforcing correct engagements, the panel helps children to figure out what they are doing wrong if they make mistakes—allowing for trial and error in a fun and friendly way.

STEMosaur’s easy-to-use coding panel teaches graphical programming and computational fluency while allowing kids to unleash their creativity and program their STEMosaur to tell unique jokes and new stories of their own making.

When kids apply the code they’ve created to their STEMosaur , they are rewarded with new conversations and possibilities—providing early learners with the perfect way to stay engaged and excited about education!

The parent panel makes it easy for parents to be a part of the learning journey every step of the way. This secure, web-based dashboard provides insights into what kind of questions kids are asking their STEMosaur, and even enables adults to customize bedtime settings and monitor usage patterns.

Parents can also play a part in their child’s education by contributing to the development of STEMosaur by submitting content ideas and other recommendations through the parent panel.

STEMosaur is powered by Elemental Path’s proprietary Friendgine technology - the only A.I. built specifically for kids.

User experience is enhanced by features such as:

Meet the DINOmite team that developed STEMosaur! These learning lovers and toy-building experts put their heads together to bring this conversational, fun and educational toy and its “Friendgine” technology to kids and their families everywhere.

Thanks to the support of people like you, STEMosaur is already in production. Here's a quick look behind the scenes at our new packaging. Our creative team at CogniToys thought long and hard before creating the final version you see below, so we hope you love it as much as we do!

What is the recommended age range for STEMosaur?

We recommend STEMosaur for kids aged 7 and up. However, with the help of an adult, a child younger than 7 will also enjoy the toy.

Do I need to be connected to wifi to use my STEMosaur?

Yes, you need to be connected to wifi when you are using your STEMosaur. However, once your toy is set up it will stay connected to your home network so you don't have to go through the process of connecting your STEMosaur all over again.

Via app - available via iOS and Android

What are the STEMosaur'sdimensions?

5.5” L x 4” W x 7” H

How much does it weigh?

Approx. 1lb

Is my STEMosaur listening even when my child isn’t playing with it?

No! A child must press the toy’s Belly button in order for it to be capable of listening. So if you’re speaking while STEMosaur is in the room, but no one is holding the button, the toy will not pick up on anything being said.

How does my child gain access to new content?

Every week our in-house content team sends new content via over-the-air-updates that will update automatically when a child turns on their STEMosaur. No additional action is required for these updates by the parent or child. We regularly add new stories, jokes, games, and more to keep the toy interesting.

Does STEMosaur speak any other languages?

Currently, STEMosaur only speaks and understands English.

*STEMosaur also caters for variances in accent via our speech recognition software e.g. British, Australian, etc.

Can two or more kids share one STEMosaur?

Absolutely! STEMosaur makes playtime fun for everyone. However, please keep in mind that STEMosaur cannot differentiate between voices and only retains information for a single user.

What will the STEMosaur do if a child asks an inappropriate question or uses profanity?

“It’s not polite to say that!” - Our child-friendly filters ensure each and every STEMosaur protects kids from content that is unsuitable and inappropriate.

What is the Parent Panel?

The Parent Panel is a secure, log-in only dashboard where parents can view learning metrics, edit account settings and access the coding panel. In the not so distant future parents will also be able to add additional product features through the parent panel.

Do CogniToys collect kids’ data? How safe is the toy?

Privacy is our top priority. We collect only the information necessary to improve the overall play experience. For example, when kids ask questions the STEMosaur doesn’t know, our content team receives an anonymized report to ensure that answers for these questions are added in the future. Data obtained from children is only retained for the amount of time necessary to improve the STEMosaur play experience. It is then deleted, though the statistical analysis remains. Parents can always remove all data collected at any point by resetting the toy through the CogniToys App. We do not sell any information, whether child-generated or received from parents, to 3rd parties.

Does my child need to know how to code to use the coding panel?

No - no previous coding experience is required to use and enjoy the coding panel. The coding panel is easy to navigate and contains instructions and examples to help kids learn how to code content into their very own STEMosaur.

Does my child need access to a computer to use the coding panel?

Yes, a computer with working wifi is required to access the coding panel.

The coding panel can be accessed through the parent panel.

How difficult is it to construct STEMosaur?

Kids can build their STEMosaur from scratch with help from the construction guide included.However, STEMosaur is a toy for the whole family and we encourage parents to actively engage in the construction and use of STEMosaur.

Is it easy to connect STEMosaur to WiFi?

If you have any trouble we have easy to follow guides and videos on our website.

Do you ship internationally?

Yes. Shipping costs vary depending on the country, but we do ship internationally.

Does STEMosaur come with any other voices?

We plan to allow a child to choose a custom voice for their STEMosaur from the coding panel.*This feature may be rolled out after our Indiegogo campaign.

What will my child learn from their STEMosaur?

In addition to engineering and coding, STEMosaur helps kids learn everything from math and science to geography and history. Our experienced content team also send out weekly updates with new and relevant content to ensure your STEMosaur gets smarter with every update. You can also learn more about how to play with your STEMosauron the Commands page on our website.

Does STEMosaur come in any other colors?

Not right now.

Can STEMosaur be taken apart once built?

To avoid excessive wear and tear we do not recommend that STEMosaur be taken apart once assembled.

Do you have helpful advice on how to troubleshoot?

We have many ways for you to learn about your STEMosaur - from the FAQ section on our website to our friendly customer service team who can be contacted at Buy Cheap Countdown Package Largest Supplier SFDONNA Trainers black Outlet Best Place Sale With Mastercard Outlet Reliable A3ar3
. Be sure to also check out the Quick Start Guide included to learn more about what your CogniToy is doing.

Speech Recognition

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CEO of smart-toy startup credits time in the Marine Corps Reserves for skills he took to the tech and toy industries.

Mike Sorrentino

To Donald Coolidge, veterans are a lot like MBA students, which makes them great candidates for the startup space.

"They are really good at making decisions quickly, and without a lot of information available, which in the startup world is extremely helpful," said Coolidge, who has successfully applied his US Marine Corps Reserve training to the market battle in the AI toy arena.

Coolidge, 30, is CEO of an internet-connected toy company called Elemental Path. He served nine years in the Marine Corps Reserves, including a deployment in Iraq. While transitioning from the armed forces back to civilian life can often be a difficult battleground for veterans , Coolidge said being in the reserves kept him rooted in both lifestyles.

"I was always one foot in the military, one foot in civilian life," Coolidge said, noting that aside from the deployment into Iraq, his transition wasn't as extreme as it could be.

The CogniToys Dino is the first product from Elemental Path, a company whose CEO is a veteran of the Marine Corps Reserve.

"When I came back from Iraq, I started to get into the nonprofit world for veterans," Coolidge said. "I think that did help with that transition process, and that's sort of how I got into the tech industry because one of the Marines in my unit was a computer science guy."

While not a coder by profession, working with that other Marine got him started with building products in the tech world. He credits his time in the Marines for giving him management experience at a young age that he's taken with him.

"When I was 20, 21, I had responsibilities that were far beyond what I would of had if I didn't serve," Coolidge said, which included supervising younger Marines and handling equipment. And he learned how to react fast.

He and his co-founders, Sean O'Shea and JP Benini, applied that speed when they took the CogniToys Dino toy from Kickstarter to product. Elemental Path was founded in August 2014, launched its Christian Louboutin Eelskin PeepToe Pumps Low Cost Manchester Online Big Sale Cheap Price Sale Professional Wiki Sale Online ctIN4WOj
in February 2015 and launched the first wave of the Dino toy later that year.

Talking holiday toys that can become your kid's digital friend

"About a year or so after we launched the company, we were actually pushing Dinos out into the public," he said.

The Dino is similar to the Amazon Echo speaker in some ways: It connects to a Wi-Fi network and when a child speaks to it, the toy answers questions and plays games. Unlike the original Echo, the toy only listens in when a button on the Dino's stomach is pressed.

The following are some of the other key features of a smartphone:

A smartphone also has the ability to support accessories, including 31 Phillip Lim Embellished CapToe Oxfords Cheap Prices Authentic Visit New For Sale FUN4p6v7S
headphones, power charging cables and extra speakers. Because of the fragile outer casing of most smartphones, users often also purchase screen protectors and more durable cases in which to put their phones.

Because they run an OS and applications, smartphones get consistent software updates. Vendors update their mobile OSes a few times a year, and individual mobile apps in an app store see constant software updates that users can either choose to install or ignore.

Mobile OSes include Apple iOS, Google Android, Microsoft Windows Phone and BlackBerry 10. BlackBerry said it will discontinue its OS in 2019, however, and Microsoft has long been a distant player in the mobile OS race.


The top smartphone hardware manufacturers are Apple, Samsung, Huawei, LG, Lenovo -- including Motorola -- Oppo and several others. Apple is the only vendor that builds the iPhone for its iOS operating system. Multiple manufacturers can produce Android devices.

As of April 2018, Android leads the OS market share worldwide with about 40% of the market, according to StatCounter.

Many consumers use their smartphones to engage with friends, family and brands on social media.

Social media platforms such as Facebook, Instagram, Twitter and LinkedIn all have mobile apps that a user can download from their phone's app store. These apps make it easier for smartphone users to post personal updates and photos while on the go rather than at their desktop.

Another common use for smartphones is health and wellness tracking. The Health app for iOS, for instance, can keep track of sleep behavior, nutrition, body measurements, vital signs, mental health exercises and more.

Third-party wearable devices, such as smartwatches, can connect with a smartphone to monitor an individual's health statistics, such as heart rate, and send information to be aggregated on the phone.

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is another popular use for smartphones. Wallet features allow users to save credit card information on their phones to use when purchasing items at retail stores. Apps such as Apple Pay also enable users to pay other iOS users directly from their phones.

BlackBerry devices were the first popular smartphone many organizations offered to their employees for business use due to BlackBerry's history with strong security. As smartphones added more advanced productivity features, security techniques and integrations with IT management tools, others gained popularity in the enterprise.

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How can enterprise users get work done with smartphones?

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IT professionals in many organizations today must support employees that want to use their smartphones for work. Businesses can adopt enterprise mobility management (EMM) tools to control this use and develop BYOD policies to govern what users can do with their devices. Apple and Google have both worked to improve the enterprise capabilities of their mobile OSes, enabling IT to better support iPhone and Android devices in businesses.

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